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Name of Journal: Advance Pharmaceutical Bulletin
Various floating and pulsatile drug delivery systems suffer from variations in the gastric transit time affecting the bioavailability of drugs. The objective of the study was to develop Pantoprazole Sodium (PAN) microballoons that may prolong the gastric residence time and could enhance the drug bioavailability. This kind of pH dependent drug delivery may provide an efficient dosage regimen with enhanced patient compliance.