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This review article on Cycas revoluta mainly comprehensively summarizes characterization, morphology, distribution, traditional uses, phytochemical constituents and biological activities of isolated individual constituents as well as plant extract. Cycas revoluta is commonly known as Sago palm which belongs to gymnosperm species, cycadaceae family and has been used as a traditional medicine to cure blood vomiting, flatulence, skin diseases, hypertension, gastrointestinal distress, cough, blood pressure, hair growth, astringent, diuretic, snake bite, dressing wounds, swollen glands and stomach purifying. Its phytochemical analysis have been revealed the presence of flavonoids, glycosides, non-protein amino acids, fatty acids, benzenoids, terpenes, amino acids, diterpenoids, triterpenoids, sterols, esters and steroids. The chemical constituents and crude extracts exhibit biological activities such as antimicrobial, antioxidant, cytotoxic, antileishmanial, anticancer and many more.

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